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Morpholinophosphorothioamidite

Utilization methods and advantages of morpholino chlorophosphoramidite.

Introduction to High Purity Morpholino Chlorophosphoramidite As gene therapy and antisense drug development open up new possibilities in medicine, the key to their success lies in the high-performance artificial nucleic acid known as Morpholino Oligomer (PMO). Sapala Organics combines years of expertise in nucleic acid chemistry with cutting-edge technology to provide high-quality Morpholino synthesis reagents that strongly support your next-generation oligonucleotide drug development. What is Morpholino? Morpholino Oligomer (PMO) is a type of artificial nucleic acid that replaces the sugar (ribose) backbone of natural nucleic acids with a Morpholino ring, and the ionic phosphodiester bond with a non-ionic phosphorodiamidate bond.

  • Custom reactions and synthesis
  • Nucleic Acid Synthesis Reagents

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PNA (Peptide Nucleic Acid) synthesis

What could not be detected with DNA so far can be detected with PNA! Please consider it at least once.

"PNA (Peptide Nucleic Acid)" is a non-natural compound with a DNA-like structure. Its structure differs from that of DNA and RNA, as it forms a backbone with peptide bonds instead of phosphate bonds, which is why it is called peptide nucleic acid. It has excellent properties as an antisense and probe. The repulsion caused by the negative charge from phosphate groups found in conventional DNA is eliminated, allowing for stronger hybridization and improved complementary strand recognition. Additionally, "PNA synthesis" is entrusted to the South Korean company Panagene. For a formal estimate, please send us information such as the sequence and desired yield, and we will confirm the feasibility of synthesis with Panagene. *For more details, please refer to the related links or feel free to contact us.*

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  • Nucleic Acid Synthesis Reagents

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